South Carolina's hospitals range from large academic and multi-hospital systems in Columbia, Charleston and Greenville to small community hospitals that serve a single county seat. This page sorts them by city and county so you can find the closest facility, check its address and call before you travel. Below, we explain how hospital care is organized in the state, who regulates it, and what to expect when you arrive.

How Hospital Care Is Organized in South Carolina

Most hospital care in the state is delivered through regional systems rather than stand-alone buildings. Prisma Health runs a large network across the Upstate and Midlands, including its Greenville and Columbia campuses. MUSC Health, built around the Medical University of South Carolina, anchors Charleston and is the state's main academic medical center. McLeod Health is the dominant system in the Pee Dee, with its flagship in Florence. Smaller systems and independent hospitals fill in the rest, including AnMed in Anderson, Self Regional Healthcare in Greenwood, Conway Medical Center in Horry County and Kershawhealth in Camden.

Names in a directory do not always match the signs on the building. A listing such as Ghs Greenville Memorial Hospital at 701 Grove Road reflects the old Greenville Health System name, which is now part of Prisma Health. When a name looks dated, check the address and call the main number to confirm.

Not every listing is a general emergency hospital. The South Carolina records include several other types:

Knowing which type you need saves time. A dialysis unit cannot treat chest pain, and a correctional infirmary cannot take a walk-in patient.

Metro and Rural Hospitals Across the Midlands, Lowcountry, Upstate and Pee Dee

South Carolina is a small state, but access to hospitals varies a great deal by region. The gap between a county with several hospitals and one with a single critical-access facility shapes where people go for care.

The Midlands: Columbia and Surrounding Counties

Columbia has more listings than any other South Carolina city. Most of them fall in Richland County, with more across the river in Lexington County, where West Columbia hosts Three Rivers Behavioral Health. The capital region also holds state-run services. Gilliam Psychiatric Hospital sits within the state's public mental health network. Outside the metro area, Kershawhealth in Camden and the Orangeburg-area listings serve small cities that depend on Columbia for the most complex cases.

The Lowcountry and Coast

Charleston is the region's medical hub. Charleston County includes downtown campuses, East Cooper Medical Center at 2000 Hospital Drive in Mount Pleasant, and the rehabilitation hospital in North Charleston. Daniel Island Medical Center, at 900 Island Park Drive, is listed under Charleston but lies in Berkeley County, so check the county before you search by jurisdiction. Farther south, Beaufort County includes Naval Hospital Beaufort at 1 Pinckney Boulevard, which serves military families through TRICARE. Along the Grand Strand, Horry County relies on Conway Medical Center on Singleton Ridge Road. Coastal hospitals plan for hurricane season, and visiting rules can change quickly when evacuations are ordered.

The Upstate

The Greenville-Spartanburg corridor has the densest concentration of hospitals outside Columbia and Charleston. Greenville County includes Greenville Memorial, Allen Bennett Memorial Hospital in Greer and Springbrook Behavioral Health in Travelers Rest. Spartanburg has its own cluster, including the Mary Black Health System listing on Skylyn Drive. Anderson is served by AnMed Health Medical Center on North Fant Street. Patients in smaller Upstate towns such as Abbeville, with Abbeville Area Medical Center on Thomson Circle, often travel to these larger campuses for surgery or specialist care.

The Pee Dee and Rural Interior

The Pee Dee depends heavily on Florence County, where McLeod Regional Medical Center acts as the referral center for several surrounding counties. Smaller hospitals such as McLeod Health Cheraw, Marlboro Park Hospital in Bennettsville and Chester Regional Medical Center handle emergencies, inpatient basics and routine care. They typically transfer trauma, advanced cardiac and neonatal cases to larger centers. In the northern part of the state, Piedmont Medical Center in Rock Hill and Springs Memorial Hospital in Lancaster draw patients from communities that also look toward Charlotte.

Who Licenses and Oversees Hospitals in South Carolina

The South Carolina Department of Public Health licenses hospitals under state regulation, with minimum standards set out in Regulation 61-16. Until mid-2024, this work belonged to the Department of Health and Environmental Control, so older documents and websites may still use that agency's name. Licensing covers physical plant safety, staffing, infection control, patient rights and emergency services. The department also takes complaints about licensed facilities.

Several other bodies shape what you see at the front desk:

Before You Go: Getting the Most From a South Carolina Hospital Visit

Call 911 for chest pain, stroke symptoms, severe bleeding, major injury or trouble breathing. Do not drive yourself if you might lose consciousness. Ambulance crews can choose a hospital with the right capability, which may not be the closest one.

For planned visits, bring the following:

Use the phone numbers and addresses on each listing page, then confirm directly with the hospital. Campuses are large, and the emergency entrance, outpatient registration and behavioral health unit are often in different buildings.

Hospitals across South Carolina provide a full range of medical services from emergency and trauma care to specialized treatment programs, with public and nonprofit facilities playing a particularly important role in serving uninsured and rural populations throughout the state.

Hospitals locations are available in 56 cities across South Carolina. They are spread across 41 counties.

Cities with the highest concentration include Columbia, Charleston, Florence, which serve as major medical centers with academic teaching hospitals, trauma centers, and specialized treatment facilities for the surrounding region.

Residents of South Carolina should know their nearest emergency room location before a medical crisis occurs, and should check their insurance network to understand which hospitals in the state are covered under their plan.

Hospitals by Counties

A
B
C
D
E
F
G
H
J
K
L
M
N
O
P
R
S
U
W
Y

Residents of South Carolina who face large hospital bills should ask about financial assistance programs before the bill goes to collections. Most hospitals are required to notify patients about charity care options, and applications can often be submitted months after a visit.

Browse Hospitals by county across South Carolina to find the nearest location.

Practical Notes for Hospital Visits in South Carolina's Coastal and Rural Counties

Geography affects hospital planning in South Carolina more than many visitors expect. On the coast, hurricane season runs from June through November. Hospitals in Charleston, Beaufort and Horry counties may restrict visitors, delay elective procedures or transfer patients when the state orders evacuations. If you depend on dialysis, oxygen or regular infusions, ask your provider for a storm plan before the season begins and keep a printed medication list in your go-bag.

In rural counties, the main challenge is distance. A small hospital such as Abbeville Area Medical Center or Chester Regional Medical Center can stabilize an emergency, but you may be transferred by ambulance or helicopter to a larger center in Greenville, Columbia or Charleston. Ask early about transport and which hospital will receive you, so family members know where to drive.

Many listings are tied to larger organizations, and their phone numbers may reach a central operator rather than a front desk. Say the department you need, such as emergency, admitting, medical records or billing. If the listing shows no phone number, as with some federal facilities, check the facility's official website or contact the sponsoring agency before traveling.

The South Carolina Department of Public Health licenses hospitals under Regulation 61-16, which sets minimum standards for facilities and staffing. Before the 2024 reorganization, that responsibility sat with the Department of Health and Environmental Control, so older forms and web pages may still use that name. If you have a complaint about patient care, cleanliness or safety at a licensed hospital, you can file it with the department's healthcare quality staff. For Medicare billing or quality concerns, contact the federal Medicare program or the hospital's own patient advocate.

The highest-level trauma care is concentrated in the three largest metro areas. MUSC in Charleston, Prisma Health Greenville Memorial in Greenville, and Prisma Health Richland in Columbia are the best-known Level I centers. Smaller hospitals, including those in Florence, Spartanburg and Anderson, handle many injuries and stabilize patients who need transfer. In an emergency, call 911 and let the crew decide the destination. They follow state trauma protocols and may bypass a nearer hospital if your injuries need a higher level of care.

Federal law requires any hospital with an emergency department that takes Medicare to screen and stabilize you, whatever your ability to pay. Afterward, ask the billing office for the hospital's financial assistance application. Nonprofit hospitals must have a written financial assistance policy under federal tax rules. You can also check eligibility for Healthy Connections, South Carolina's Medicaid program, through the Department of Health and Human Services. The state has not adopted the full Medicaid expansion, so eligibility for adults without children is limited. Apply as soon as possible, because coverage can sometimes apply to recent bills.

Naval Hospital Beaufort, at 1 Pinckney Boulevard, is a military treatment facility. It mainly serves active-duty personnel, their families, and retirees who are enrolled in TRICARE or otherwise eligible for military health benefits. Visitors typically need a valid military or dependent ID and must pass base access procedures. If you are not eligible, use one of the civilian hospitals in Beaufort County or nearby counties. Eligible patients should call ahead to confirm clinic hours, referral rules and whether an urgent condition should go to a civilian emergency department.

Call or text 988, the national Suicide and Crisis Lifeline, or call 911 if someone is in immediate danger. A hospital emergency department can evaluate a crisis and arrange admission if needed. Psychiatric facilities in our listings include Gilliam Psychiatric Hospital in Columbia, Three Rivers Behavioral Health in West Columbia and Springbrook Behavioral Health System in Travelers Rest. Admission to these facilities is often arranged through an evaluation or referral, so call first rather than showing up unannounced. The state Department of Mental Health also operates community mental health centers in each region.

Contact the hospital's medical records or health information management department, which may be separate from the main switchboard. Federal HIPAA rules give you a right to see and copy your records. Expect to submit a signed written request and show photo ID. Hospitals generally must respond within 30 days, and may charge only a reasonable, cost-based fee for copies. Many larger systems, including those in Greenville, Charleston and Florence, also offer patient portals for faster access to test results and discharge summaries. If you are requesting records for another person, bring proof of legal authority.